The CYP19A1 gene encodes the enzyme aromatase, which is responsible for the biosynthesis of estrogens. The rs 10046\npolymorphism of CYP19A1 gene has been investigated in two studies on the occurrence of hypertension, but there are no studies on\nits correlation with coronary artery disease (CAD).We investigated 189 subjects who were hospitalized at ââ?¬Å?KATââ?¬ÂGeneral Hospital of\nAthens and underwent coronary angiography. Of these, 123 were found with CAD with an average age of 60 years and constituted\nthe patients group and 66 subjects with an average age of 58 years without damage in the coronary vessels and constituted the\ncontrol group (healthy). The frequencies of genotypes CC, CT, and TT of rs10046 polymorphism are significantly different between\nthe group of CAD patients and the control group (0.34, 0.48, and 0.18 versus 0.20, 0.48, and 0.32, resp.,
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